German airline Lufthansa said on Friday that it would resume flights from Frankfurt to Tehran from April 16.
Lufthansa had suspended flights in January 2020 after a Ukranian airliner was shot down soon after take-off from Tehran.
The airline said it has since assessed security measures by Iran with national and international authorities.
“The conditions for safe flight operations in Iranian airspace are currently in place,” it said in an emailed statement.
Iran’s Revolutionary Guards shot down the Ukraine International Airlines flight with ground-to-air missiles on Jan. 8, 2020 shortly after it took off from Tehran.
The Iranian government later declared that the shooting down was a “disastrous mistake” by forces who were on high alert during a regional confrontation with the United States.
Iran was on edge about possible attacks after it fired missiles at Iraqi bases housing US forces in retaliation for the killing days before of its most powerful military commander, Qassem Soleimani, in a US missile strike at Baghdad airport.