Coronavirus: Interval between COVID-19 vaccine doses should be respected, says EU

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The European Medicines Agency said on Monday that the maximum interval of 42 days between the first and the second dose of the Pfizer-BioNtech vaccine should be respected to obtain full protection.

Evidence of the vaccine efficacy is based on a study where administration of doses was done 19 to 42 days apart, the agency said, noting that full protection comes only seven days after the booster.

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It added: “Any change to this would require a variation to the marketing authorization as well as more clinical data to support such a change, otherwise it would be considered as ‘off label use’.”

Off label use entails lower liabilities on vaccine makers.

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