Chinese data from COVID-19 early days gives crucial information on origins

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Data from the early days of the COVID-19 pandemic, briefly uploaded to a global database by Chinese scientists, gives crucial information on the outbreak’s origins, including of an animal market in the Chinese city of Wuhan, researchers said.

The virus was first identified in Wuhan in December 2019, with many suspecting the Huanan live animal market to be the source, before spreading round the world and killing nearly 7 million people.

The scientists published a pre-print report based on their interpretation of the data on Monday, after leaks in the media last week and a meeting with the World Health Organization, which has urged China to release more information.

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The data from the Chinese Center for Disease Control and Prevention (CDC) is no longer available on the GISAID database where it was found by the scientists.

It comprised new sequences of the SARS-CoV-2 virus and additional genomic data based on samples taken from a live animal market in Wuhan in 2020, according to the scientists who accessed it.

The sequences showed that raccoon dogs and other animals susceptible to the coronavirus were present in the market and may have been infected, providing a new clue in the chain of transmission that eventually reached humans, they said.

“This adds to the body of evidence identifying the Huanan market as the spillover location of Sars-CoV-2 and the epicenter of the COVID-19 pandemic,” said the report.

It was written by authors including the University of Arizona’s Michael Worobey, Kristian Andersen of Scripps Research in La Jolla, California, and Florence Débarre at the Sorbonne University in Paris, France, who accessed the data.

In comparison to the leaked information last week, the report adds more detail about other animals present at the market, as well as showing that some of the SARS-CoV-2 positive environmental samples had more animal than human genetic material in them, which the researchers said was consistent with the animals being infected.

WHO officials said last week that the information was not conclusive but did represent a new lead into the investigation into COVID-19’s origins, and should have been shared immediately.

The UN agency has previously said that all hypotheses for COVID-19’s origins remain on the table, including that the virus emerged from a high-security laboratory in Wuhan that studies dangerous pathogens.

China denies any such link. WHO has also said that most evidence points toward the virus coming from animals, likely bats.
The Chinese CDC was not immediately available for comment.

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