The closure of the border is seen as particularly significant, threatening the import of materials needed by Qatar to complete its US$200 billion-plus (S$276 billion) worth of infrastructure projects in readiness for 2022.
One construction manager told AFP that they only have materials available for two more weeks, but Qatari government ministers have claimed the country's construction industry could survive for up to a year under current conditions.
Qatar's World Cup preparations continue "as normal" and organizers remain confident that stadium construction deadlines will be met, a source close to the 2022 tournament has told AFP.
Earlier this year, Qatar revealed it is spending almost US$500m every week on for football's biggest tournament.
The crisis has also raised major concerns of yet further instability in the Middle East.
Another implication is that Qatar has promoted 2022 as a regional World Cup, to bring together fans across the Middle East.
Qatar is in almost daily contact with Fifa but that is normal, a source told AFP.