United States has found its first cases of a potent coronavirus variant first detected in South Africa, health officials in the state of South Carolina said on Thursday.
Viruses mutate frequently, and several mutated viruses have been identified. The presence of the South African variant in the United States is especially concerning because several laboratory studies have shown that it reduces vaccine effectiveness.
Another concern, according to the nominee for US surgeon general, is that the South African variant could require larger doses of antibody for treatment.
“The thing that’s troublesome now that we really need to keep our eye on are these variants,” Anthony Fauci, the leading US infectious disease specialist, said in an interview on MSNBC. “The one that is of greater concern and that really could be problematic is the mutant that is now dominant in South Africa.”
So far, vaccines made by Moderna and Pfizer/BioNTech appear protective against this variant of the coronavirus, despite the weaker response.
The companies this week said they are considering making new versions of their shots just in case. Moderna also plans to test giving a third shot of its vaccine to bolster antibody levels.
The US Centers for Disease Control and Prevention said in a statement that it is aware of the cases and noted that there is no evidence the variant causes more severe disease.
The arrival of the South African variant follows predictions by the CDC this month that a more-transmissible UK variant could become the dominant strain in the United States by March.
The South Carolina Department of Health and Environmental Control said the two cases of the B.1.351 variant of South African origin appear to be unrelated to one another.
The department said neither of the two adults had a travel history that would account for the infection.
Although the variant has been detected in more than 30 countries, the South Carolina cases were the first in the United States, it said.
The CDC has said the arrival of more transmissible coronavirus variants emphasizes the need for rapid rollout of the vaccine to limit the ability of the virus to continue mutating.
Fauci said the US had a “very serious issue” in the number of infections but was seeing some good news in plateauing cases and efforts to ramp up vaccinations.
Another variant originally detected in the United Kingdom, called B.1.1.7, has been detected in at least 28 states, according to CDC data.